PRE by the iO Clinic Estra Balance 1.75 oz frosted glass pump bottle for estrogen-deficient menopausal skin.
pre EstraBalance by The iO Clinic x SGMD - set of three
PRE Estra Balance 50 g product image
pre EstraBalance by The iO Clinic x SGMD
PRE by the iO Clinic Estra Balance 1.75 oz frosted glass pump bottle for estrogen-deficient menopausal skin.
pre EstraBalance by The iO Clinic x SGMD - set of three
PRE Estra Balance 50 g product image
pre EstraBalance by The iO Clinic x SGMD

PRE Estra Balance 50 g

Skin Types: Normal, Dry, Sensitive
Price
Regular price
$220.00 USD
Sale price
$220.00 USD
Regular price
Judgment: chosen by surgeons who see thousands of outcomes, not by a buyer or an algorithm.
Authenticity: authorized channel, direct from the brands, no gray-market risk.
Continuity: the care doesn't stop when the patient leaves the practice.

About pre estra balance

Brought to you by gynecologist Dr. Sally Greenwald and facial plastic surgeons Drs. David Lieberman and Sachin Parikh, pre estra balance features plant-based phytoestrogens to safely restore vitality and skin elasticity to estrogen-deficient skin.
Formulated to support the visible signs of estrogen-deficient skin, this nourishing balm combines plant-derived phytoestrogens, biomimetic peptides, and replenishing lipids to deeply hydrate and reinforce skin structure. Phytoestrogens act locally in the skin without meaningfully stimulating other estrogen-sensitive tissues, which makes it safe for all women to use.
Soybean seed extract provides naturally occurring isoflavones, which have been studied for their role in supporting skin firmness and collagen integrity as estrogen levels decline.
A growth factor and synergistic blend of peptides helps promote skin renewal and resilience, while niacinamide, stabilized vitamin C, vitamin E, and ferulic acid deliver antioxidant protection and tone refinement. Rich emollients, ceramides, and squalane restore barrier function for improved comfort and radiance. The formula is paraben-free, aligning with the preferences of women seeking a thoughtfully formulated approach to skin vitality.

Size:

1.75 oz / 50 g
  • Backed by three double board-certified physicians - Drs. Sally Greenwald, David Lieberman, and Sachin Parikh
  • Rich in plant-based phytoestrogens, which provide the skin benefits of estrogen signaling, without systemic activation
  • Paraben-free, an important consideration for women seeking to minimize exposure to potential endocrine disruptors
  • Fragrance and dye-free
  • Growth factors support skin regeneration, repair, and collagen production

pre estra balance can be used for:

  • Normal, dry, or combination skin
  • Estrogen-deficient skin
  • Photoaged, sagging skin
  • Uneven skin tone
  • Skin unable to tolerate retinoids

How to Use pre estra balance


estra balance is best used in the morning as your first product.* Because it also contains advanced forms of vitamin C and ferulic acid, estra balance can replace your morning antioxidant serum. Finish with a mineral-based SPF. If you're looking for a complementary nighttime product, consider Plated Intense.

*Always consult your medical provider before incorporating a new skincare product.

PRE Estra Balance 50 g

Frequently Asked Questions

Answer by skin type, concern, and routine role.

Keep conservative: “Follow your provider’s post-care instructions. This product may be appropriate for some post-treatment routines depending on your skin and procedure.”

AM, PM, or both. Mention order of application.

Cross-sell cleanser, serum, moisturizer, SPF, or recovery product.

Include patch-test or provider-guidance language.

Useful for price justification.

Brief policy, especially for unopened products.

About Us

Why shop with iO Shop

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    Harness the power of advanced molecular technology in our formulas, delivering targeted benefits for smoother, healthier skin.

The Results Are In

Discover visible skin changes and impressive results

L&P Aesthetics has been at the forefront of facial plastic surgery in Northern California for over a decade. The iO Clinic was built on the same belief: that the level of care our patients receive does not have to stop when they leave. Every product here has been chosen by our clinical team.

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"I started using the Recovery Crème after my laser treatment on the recommendation of my surgeon. My skin settled so much faster than after my previous procedure. I have been back for two more tubes since."ZO Skin Health Recovery Crème, Sarah M

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PlatI found the iO Clinic through a friend and ordered the Plated Intense Serum without ever visiting in person. Three months in, the texture of my skin is genuinely different. I have tried a lot of serums. This one I kept." Intense Serum, Jennifer L

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“My dermatologist had mentioned Alastin but I never knew where to buy it. The fact that a surgical team is behind the recommendation here made it easy to trust. My skin has been noticeably calmer and firmer in about six weeks." Alastin Skincare Restorative Skin Complex, Rachel T.

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