Jan Marini Night Zyme overnight resurfacing complex in a sage green squeeze tube.
Jan Marini Night Zyme overnight resurfacing complex in a sage green squeeze tube.

Marini Skin Solutions - Night Zyme

A gentle enzymatic overnight resurfacer that polishes and hydrates without acids, layering over any PM routine.
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$115.00 USD
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$115.00 USD
Regular price
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Judgment: chosen by surgeons who see thousands of outcomes, not by a buyer or an algorithm.
Authenticity: authorized channel, direct from the brands, no gray-market risk.
Continuity: the care doesn't stop when the patient leaves the practice.

Marini Skin Solutions Night Zyme is an overnight resurfacing treatment that uses proteolytic enzymes rather than acids. Enzymes digest the protein bonds holding dead surface cells in place, which produces a polished result without the pH shift and irritation potential of an acid.

That distinction makes it usable by people who cannot tolerate glycolic or salicylic acid, and it means it can be layered over any existing nighttime routine rather than replacing part of it.

Alongside the enzymes, the formula includes peptides and advanced hydrators to refine texture, reduce the appearance of pores, restore radiance, and support skin barrier health overnight. It suits all skin types and is gentle enough for everyday use.

1. Complete your usual evening routine.
2. Apply Night Zyme as the final step, over everything else.
3. Leave on overnight and rinse in the morning as part of your normal cleanse.
4. Use nightly, or three to four nights a week if you prefer.

Because it is enzymatic rather than acidic, it can be used alongside a retinoid, though sensitive skin may prefer alternate nights while adjusting.

Proteolytic Enzymes: digest the protein bonds holding dead surface cells in place, providing gentle resurfacing without acids.

Peptides: support skin structure and the appearance of firmness alongside the resurfacing.

Advanced Hydrators: boost hydration for smoother, more nourished skin and offset any dryness from resurfacing.

Barrier-Supporting Agents: maintain skin barrier health through overnight use.

• Improves texture for a polished, glass-like finish.
• Boosts hydration for smoother, more nourished skin.
• Enhances luminosity for better light reflection and glow.
• Reduces the appearance of pores.
• Supports overall healthy-looking skin and barrier health.
• Gentle enzymatic resurfacing suitable for everyday use.
• Layers over any existing nighttime routine.

Enzymatic exfoliation is underused and worth understanding. Enzymes work on protein bonds and do not require a low pH, so they exfoliate without the stinging, flushing, and barrier disruption that acids can cause. For patients with rosacea, reactive skin, or a damaged barrier, that is a meaningful advantage.

Our providers recommend it particularly to patients who have over-exfoliated with acids and need to step back without giving up resurfacing entirely, and to patients who cannot tolerate glycolic acid at all.

Because it layers over an existing routine, it also solves a practical problem: no rearranging, no incompatibilities. Order it here at any time. If you would rather talk it through first, call (650) 508-6565.

Marini Skin Solutions - Night Zyme
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